Our distinct model platform combines human endothelial cells, immune cells and vascular flow to study inflammatory responses in biologically relevant conditions, enabling more predictive inflammatory drug profiling. By generating reliable, translational insights earlier in the development, we help you reduce risk and make better-informed decisions.
We have developed a proprietary human tissue-based flow system that captures key physiological features of inflammation. Using live bio-imaging, we measure:
Recruitment
Movement of leukocytes through vascular barriers
Retention
Persistence of immune cells within inflamed tissue
Inflammation control (anti-/pro-inflammatory setups)
Standardized vascular flow simulation
Personalized medicine – fresh donor blood from Swiss-certified source
Multiple cell formats (whole blood, purified leukocytes, cell lines)
Circadian cycles compatibility
01.
.webp){kind=spacer}
Cell Adhesion Model
Our adhesion model measures the strength of cell attachment using the controlled detachment assay, and static migration assay. This platform delivers reproductible analysis of cell adhesion dynamics starting with defined ligands through to migration dynamics in extravascular tissue models.
➔ Immune cell profiling
➔ Adhesion mechanism assessment
➔ Leukocyte kinetics in static tissue cocultures
LEARN MORE
.webp){kind=spacer}
Inflammation Model
Our inflammation model recreates acute or chronic inflammatory states in human endothelial cells. This platform enables evaluation of compound efficacy and a reliable way to study inflammatory responses in a vascular micro-environment.
➔ Leukocytes trafficking
➔ Vascular modeling
➔ Mechanism of action (MoA)
LEARN MORE
Tumor-Targeting Model
Our tumor-targeting model provides predictive insights into how immune cell activation drives anti-tumor efficacy. It enables precise assessment of immune-mediated tumor targeting in a human-relevant settings.
➔ CAR-T and B-cell therapies efficacy testing
➔ Cancer therapeutics and treatment
➔ Mechanisms of action (MoA)
LEARN MORE
.webp){kind=spacer}
Organoid Model
Our vascularized organoid modelrecreates complex tissue micro-environments to study leukocyte trafficking and endothelial interactions. Integrating proprietary organoid components into our vascular models offers deeper insights into cell behavior and improves predictive power of preclinical studies.
➔ Tissue and vascular modeling
➔ Organ-specific drug testing
➔ Complex physiological interactions
LEARN MORE
02.
Buffy Coat
Leukocyte concentrate delivered from Swiss-certified source, processed within 24 hours
Fresh Blood
Same day collection
and processing
Blood cells can be used as a whole blood or as purified population.
03.
Basophil
Eosinophil
Neutrophil
Natural killer cell
Platelet
(resting or activated)
Monocyte
B-cell +
all subsets
T-cell +
all CD4 and CD8 subsets
Activated T-cell
(IL-2 culture)
Cell types from other sources:
Provided by client
CAR-T cell
Cancer cell
Stem cell
Cell lines
From a patient
Sickle red blood cell
MesenFlow Technologies SàrlChemin des Aulx 14
1228 Plan-les-Ouates
Geneva, Switzerland
+41 22 32 16 961 (office)
+41 79 36 66 291 (mobile)